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D. E. Shaw Research seeks early-career scientists and engineers to join our New York–based team as summer interns. Roles are available for applicants of varied backgrounds and experience levels, from sophomores in college to graduate students. Successful candidates will have impressive records of academic achievement in the natural sciences and/or scientific software development.


D. E. Shaw Research is pursuing long-term projects aimed at fundamentally transforming the process of drug discovery. Our group has shed new light on biomolecular phenomena such as protein folding, protein dynamics, and protein-drug interactions by directing unprecedented computational power toward the solution of key problems in the fields of biomolecular simulation and design. 


Interns spend 12-15 weeks working closely with members of our hardware, software, or chemistry teams on a substantial engineering or research project. Past interns have contributed to compiler or software development for our ANTON® supercomputers, large-scale data management and analysis tools, visualization software, simulation software for commodity clusters and GPUs, machine learning initiatives, or any range of other projects integral to our research objectives. Throughout the summer, interns are invited to participate in a seminar series led by members of our technical team and in lively social programming. We provide our interns with above-market compensation and a generous housing allowance.


If you are interested in exploring groundbreaking research topics with the mentorship of our world-class, interdisciplinary team of biologists, chemists, and computer scientists, please use the link below to submit your application materials: (We accept applications on a rolling basis throughout the calendar year)



We will be hosting a virtual information session that will offer you an opportunity to learn more about D. E. Shaw Research and our research and engineering projects (details below). We will also briefly talk about the full-time and internship opportunities in our group so please mark your calendar accordingly. 


D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse workforce. We welcome inquiries from all exceptionally well-qualified applicants, regardless of race, color, nationality, national or ethnic origin, religion or religious belief, caste, gender, gender identity, pregnancy, caregiver status, age, military service eligibility, veteran status, sexual orientation, marital or civil partner status, disability, or status in any other category protected in this regard by law in any jurisdiction in which we operate.